The easiest way to get to Siena from Florence is by bus, although the train journey is more scenic. The SITA bus from Florence’s Santa Maria Novella train station to Siena’s Piazza Antonio Gramsci takes 80 minutes. From there, Siena’s main attractions are all walkable. Note that Siena’s center is for pedestrians only. No cars are allowed (not even taxis!), so factor this in if you don’t like walking, especially if you’re not a fan of a 30° inclines. Trekking around Siena will give you some insight into how Italians can eat so much and stay fit!